Bioidentical Hormone
Replacement Therapy
I've been told my hormones are fine.
But I feel exhausted, foggy, and completely
unlike myself.
Bioidentical hormones — estrogen, progesterone, testosterone — are chemically identical to what your body already produces. Derived from plant sources and modified at the molecular level to match your biology precisely, they’re metabolized the same way as your own hormones. The goal isn’t to get you to ‘normal range’ — it’s to find what your body specifically needs to function well.
Nothing is prescribed without a comprehensive consultation and full baseline lab work first. The protocol is built around what your results actually show — not a standard template.
On this page
🔬
What BHRT is — and how it differs
👤
Who it’s appropriate for
🌿
What we investigate first
📋
How the process works
“My hormone panel came back normal. My doctor said there was nothing to treat. But ‘normal range’ and ‘what my body needs to function well’ are not the same thing.“
What BHRT Is
Hormones your body already recognizes.
Bioidentical hormone replacement therapy uses hormones that are chemically identical — at the molecular level — to those your body produces naturally. The primary hormones involved are estrogen, progesterone, and testosterone, though DHEA and thyroid hormones may also be part of a complete protocol depending on your labs.
Because bioidentical hormones match your own, the body metabolizes them through the same pathways as endogenous hormones. This typically results in better tolerability compared to synthetic hormone preparations, which use structurally different compounds that the body recognizes as foreign.
BHRT can be administered as creams, gels, patches, pellets, or oral preparations. The delivery method matters — each produces different absorption rates and blood level consistency. Dr. Jamie selects the method best suited to your specific needs and response.
How It Differs From Conventional HRT
Molecular identity, not approximation.
Conventional hormone replacement therapy typically uses synthetic or animal-derived hormones that are structurally similar to — but not identical to — human hormones. The differences at the molecular level affect how they bind to hormone receptors and how the body processes them.
Molecular identity — Bioidentical hormones bind to hormone receptors exactly as your own hormones do. Synthetic alternatives bind differently, which can produce different effects and side effect profiles.
Individualized dosing — BHRT protocols at One Tree are built from your specific lab results and symptom history — not a standard starting dose. The goal is what your body needs, not population averages.
Ongoing monitoring — Unlike some conventional approaches, BHRT at One Tree includes regular follow-up labs to track your response and adjust dosing as your body changes over time.
Transferring existing care — If you’re already on BHRT and happy with your current dosing, you can transfer your care to One Tree at follow-up appointment pricing — no need to restart the process from scratch.
Who BHRT May Be Appropriate For
Common presentations we see.
BHRT may be appropriate for a range of presentations. These are the most common at One Tree — always evaluated case by case after a full baseline lab panel.
Perimenopause & menopause — Hot flashes, night sweats, sleep disruption, mood changes, cognitive fog, vaginal dryness, and the general sense of not feeling like yourself that accompanies the hormonal shift of midlife.
Low testosterone — women — Fatigue, low libido, mood instability, difficulty building or maintaining muscle mass, and cognitive fog. Frequently undiagnosed because testosterone isn’t routinely tested in women.
Low testosterone — men — Clinically diagnosed low testosterone with accompanying fatigue, decreased libido, mood changes, or loss of muscle mass — evaluated with a full panel, not just total testosterone.
Surgical or premature menopause — Younger individuals whose ovarian function has been affected by surgery or premature ovarian insufficiency, where hormonal support has particular clinical importance.
Thyroid dysfunction — When thyroid hormone is part of the picture — evaluated with a complete panel including Free T3, Free T4, Reverse T3, and antibodies, not just TSH.
Important Considerations
BHRT isn't appropriate for everyone.
A thorough evaluation is required before any hormone therapy is prescribed. Certain medical histories require careful assessment, and some situations represent contraindications to hormone therapy.
Requires careful evaluation or may be contraindicated
History of hormone-sensitive conditions — requires case-by-case evaluation
Active blood clotting disorders or history of clots
Unexplained vaginal bleeding — requires investigation before any hormone therapy
Certain cardiovascular conditions
Liver disease affecting hormone metabolism
Dr. Jamie reviews your full medical history at the initial consultation and will be direct about whether BHRT is appropriate for your situation — or whether further evaluation is needed first.
Baseline First
Nothing is prescribed without a full picture.
Every BHRT protocol at One Tree starts with comprehensive baseline lab work. Not a standard two-marker panel — a full evaluation of your hormonal environment, thyroid function, adrenal status, metabolic markers, and the other factors that affect how hormones work in your body.
This is also why the initial consultation is two hours. Dr. Jamie reviews your full medical history, current symptoms, prior lab work, and treatment goals before any protocol is designed. The labs confirm or refine what the history suggests — they don’t replace it.
What We Investigate
Full hormone panel (estrogen, progesterone, testosterone, DHEA, cortisol) · Complete thyroid panel (TSH, Free T3, Free T4, Reverse T3, TPO antibodies) · Adrenal function and diurnal cortisol patterns · Metabolic markers (fasting insulin, glucose, lipid panel) · Sleep architecture and circadian disruption factors · Gut health’s role in hormone metabolism (estrobolome) · Nutrient status relevant to hormone production and conversion
Delivery methods
Creams & gels
Topical application — flexible dosing, absorbed through the skin.
Patches
Consistent transdermal delivery with stable blood levels.
Pellets
Subcutaneous implants providing steady release over 3–6 months.
Oral preparations
Some hormones — particularly progesterone — are well-suited to oral delivery for specific clinical purposes.
The delivery method is selected based on the specific hormone, your clinical needs, and how your body responds.
The Process
How Dr. Jamie approaches BHRT.
The protocol at One Tree is methodical by design. Baseline first, then a carefully considered plan, then monitoring at regular intervals to track your response and adjust. BHRT isn’t a set-and-forget prescription — it’s an ongoing calibration.
Free 40-Min Consultation
A conversation about your symptoms, history, and prior hormone testing. Dr. Jamie will tell you honestly whether BHRT is likely to be relevant for your situation before any commitment is made.
Initial Hormone Consultation — 2 hours
Comprehensive review of your full medical history, current symptoms, treatment goals, and any prior lab work. Baseline laboratory testing is ordered covering the full hormone panel, thyroid, adrenal function, and metabolic markers. Includes one 15-minute follow-up call once lab results are available.
Protocol Design & Start
Based on your labs and history, Dr. Jamie designs an individualized protocol: the specific hormones, dosages, and delivery methods for your case. Conservative starting doses are the rule — adjusted based on your response.
Monitoring & Ongoing Adjustment
Follow-up at 6–8 weeks to assess response and adjust dosing. Ongoing monitoring every 3–6 months initially, then annually once stable. Your protocol evolves as your body changes.
Transparent Pricing
Initial Hormone Consultation
$225
2 hours · Full history & baseline labs · Includes one 15-min follow-up call once results are available
Follow-Up Consultations
$90
60 minutes · Response review & dosing adjustment · Ongoing monitoring visits
Transferring existing BHRT care
If you’re already on BHRT, completely satisfied with your current dosing and delivery, and want to transfer your care to One Tree — we start at follow-up appointment pricing. No need to restart from scratch.
Lab costs
Lab fees are billed separately. All costs are discussed before anything is ordered — no surprise bills. Some panels may be partially coverable through your insurance depending on your plan.
Honest Expectations
What to expect — and what BHRT won't do.
Hormonal changes take time to stabilize. Most patients begin noticing improvement within 4–8 weeks of starting a protocol, but the full effect — and the fine-tuning of dosing — typically takes 3–6 months. The 6–8 week follow-up exists precisely to assess early response and make adjustments before the full monitoring cycle.
Results vary by individual — Symptom relief, the pace of improvement, and the specific hormones involved differ significantly from person to person. What works well for one patient may require a different approach for another.
BHRT works alongside lifestyle — not instead of it — Sleep, nutrition, stress, and gut health all affect hormone function. A BHRT protocol will include attention to these factors — because they determine how well the hormones work.
Not every symptom is hormonal — Some symptoms that look hormonal have other drivers — thyroid dysfunction, adrenal issues, gut-driven inflammation. The baseline investigation is designed to find the actual cause, not assume it.
This is a long-term relationship — Hormones change over time — with age, stress, health changes, and seasons. Ongoing monitoring and periodic adjustments are part of how BHRT works well over the long term.
Conditions commonly addressed
Perimenopause & menopause
Sleep disturbance & night sweats
Mood instability & brain fog
Fatigue unresponsive to rest
Low libido
Weight resistance with hormonal pattern
Low testosterone (women & men)
Thyroid dysfunction
Surgical or premature menopause
Adrenal dysregulation
“
“I had been on standard HRT for two years with partial improvement. Dr. Jamie ran a full panel, found my progesterone was still low and my T3 conversion was poor, and adjusted the protocol around what she actually found. The difference was significant — and I finally understood what was being prescribed and why.”
One Tree Patient · Colorado · Menopause & Thyroid Dysfunction
*Patient experience. Results vary. This is not a medical claim.
If you've been told your hormones are normal
but something is clearly off — that's where we start.
The free consultation is a 40-minute conversation about your history and whether BHRT makes sense for your situation. Bring any prior hormone labs if you have them. No forms, no commitment beforehand.